An efficient reagent for covalent introduction of alkynes into proteins.
نویسندگان
چکیده
A cheap and bench-stable reagent was synthesized for direct and covalent introduction of alkynes into tyrosine of target proteins, which can be further modified based on click reaction to achieve fluorescence labelling or PEGylation. This reagent should be a generally useful toolbox for chemical biology and biomaterials.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 47 شماره
صفحات -
تاریخ انتشار 2014